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Lead Optimization Studies of Cinnamic Amide EP2 Antagonists
[Image: see text] Prostanoid receptor EP2 can play a proinflammatory role, exacerbating disease pathology in a variety of central nervous system and peripheral diseases. A highly selective EP2 antagonist could be useful as a drug to mitigate the inflammatory consequences of EP2 activation. We recent...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032197/ https://www.ncbi.nlm.nih.gov/pubmed/24773616 http://dx.doi.org/10.1021/jm5000672 |