Cargando…

Polyethylene Glycol (PEG) Linked to Near Infrared (NIR) Dyes Conjugated to Chimeric Anti-Carcinoembryonic Antigen (CEA) Antibody Enhances Imaging of Liver Metastases in a Nude-Mouse Model of Human Colon Cancer

We report here that polyethylene glycol (PEG) linked to near infrared dyes conjugated to chimeric mouse-human anti-carcinoembryonic antigen (CEA) antibody greatly improves imaging of liver metastases in a nude mouse model of colon-cancer experimental metastases. PEGylated and non-PEGylated DyLight 6...

Descripción completa

Detalles Bibliográficos
Autores principales: Maawy, Ali A., Hiroshima, Yukihiko, Zhang, Yong, Luiken, George A., Hoffman, Robert M., Bouvet, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032229/
https://www.ncbi.nlm.nih.gov/pubmed/24859320
http://dx.doi.org/10.1371/journal.pone.0097965