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The Influence of 5-HTTLPR Genotype on the Association between the Plasma Concentration and Therapeutic Effect of Paroxetine in Patients with Major Depressive Disorder

INTRODUCTION: The efficacy of treatment with selective serotonin reuptake inhibitors in patients with major depressive disorder (MDD) can differ depending on the patient's serotonin transporter-linked polymorphic region (5-HTTLPR) genotype, and the effects of varying plasma concentrations of dr...

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Detalles Bibliográficos
Autores principales: Tomita, Tetsu, Yasui-Furukori, Norio, Nakagami, Taku, Tsuchimine, Shoko, Ishioka, Masamichi, Kaneda, Ayako, Sugawara, Norio, Kaneko, Sunao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032230/
https://www.ncbi.nlm.nih.gov/pubmed/24858363
http://dx.doi.org/10.1371/journal.pone.0098099