Targeting of the MYCN Protein with Small Molecule c-MYC Inhibitors

Members of the MYC family are the most frequently deregulated oncogenes in human cancer and are often correlated with aggressive disease and/or poorly differentiated tumors. Since patients with MYCN-amplified neuroblastoma have a poor prognosis, targeting MYCN using small molecule inhibitors could r...

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Detalles Bibliográficos
Autores principales: Müller, Inga, Larsson, Karin, Frenzel, Anna, Oliynyk, Ganna, Zirath, Hanna, Prochownik, Edward V., Westwood, Nicholas J., Henriksson, Marie Arsenian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032254/
https://www.ncbi.nlm.nih.gov/pubmed/24859015
http://dx.doi.org/10.1371/journal.pone.0097285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032254/
https://www.ncbi.nlm.nih.gov/pubmed/24859015
http://dx.doi.org/10.1371/journal.pone.0097285

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