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Gα(i2)- and Gα(i3)-Deficient Mice Display Opposite Severity of Myocardial Ischemia Reperfusion Injury

G-protein-coupled receptors (GPCRs) are the most abundant receptors in the heart and therefore are common targets for cardiovascular therapeutics. The activated GPCRs transduce their signals via heterotrimeric G-proteins. The four major families of G-proteins identified so far are specified through...

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Detalles Bibliográficos
Autores principales: Köhler, David, Devanathan, Vasudharani, Bernardo de Oliveira Franz, Claudia, Eldh, Therese, Novakovic, Ana, Roth, Judith M., Granja, Tiago, Birnbaumer, Lutz, Rosenberger, Peter, Beer-Hammer, Sandra, Nürnberg, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032280/
https://www.ncbi.nlm.nih.gov/pubmed/24858945
http://dx.doi.org/10.1371/journal.pone.0098325