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Gα(i2)- and Gα(i3)-Deficient Mice Display Opposite Severity of Myocardial Ischemia Reperfusion Injury
G-protein-coupled receptors (GPCRs) are the most abundant receptors in the heart and therefore are common targets for cardiovascular therapeutics. The activated GPCRs transduce their signals via heterotrimeric G-proteins. The four major families of G-proteins identified so far are specified through...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032280/ https://www.ncbi.nlm.nih.gov/pubmed/24858945 http://dx.doi.org/10.1371/journal.pone.0098325 |