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Precise genetic mapping and integrative bioinformatics in Diversity Outbred mice reveals Hydin as a novel pain gene

Mouse genetics is a powerful approach for discovering genes and other genome features influencing human pain sensitivity. Genetic mapping studies have historically been limited by low mapping resolution of conventional mouse crosses, resulting in pain-related quantitative trait loci (QTL) spanning s...

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Detalles Bibliográficos
Autores principales: Recla, Jill M., Robledo, Raymond F., Gatti, Daniel M., Bult, Carol J., Churchill, Gary A., Chesler, Elissa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032469/
https://www.ncbi.nlm.nih.gov/pubmed/24700285
http://dx.doi.org/10.1007/s00335-014-9508-0