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Smurf2 regulates hematopoietic stem cell self-renewal and aging

The age-dependent decline in the self-renewal capacity of stem cells plays a critical role in aging, but the precise mechanisms underlying this decline are not well understood. By limiting proliferative capacity, senescence is thought to play an important role in age-dependent decline of stem cell s...

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Detalles Bibliográficos
Autores principales: Ramkumar, Charusheila, Kong, Yahui, Trabucco, Sally E, Gerstein, Rachel M, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032599/
https://www.ncbi.nlm.nih.gov/pubmed/24494704
http://dx.doi.org/10.1111/acel.12195