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Smurf2 regulates hematopoietic stem cell self-renewal and aging
The age-dependent decline in the self-renewal capacity of stem cells plays a critical role in aging, but the precise mechanisms underlying this decline are not well understood. By limiting proliferative capacity, senescence is thought to play an important role in age-dependent decline of stem cell s...
Autores principales: | Ramkumar, Charusheila, Kong, Yahui, Trabucco, Sally E, Gerstein, Rachel M, Zhang, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032599/ https://www.ncbi.nlm.nih.gov/pubmed/24494704 http://dx.doi.org/10.1111/acel.12195 |
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