Aging is associated with increased regulatory T-cell function

Regulatory T-cell (Treg, CD4(+)CD25(+)) dysfunction is suspected to play a key role in immune senescence and contributes to increased susceptibility to diseases with age by suppressing T-cell responses. FoxP3 is a master regulator of Treg function, and its expression is under control of several epig...

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Detalles Bibliográficos
Autores principales: Garg, Sanjay K, Delaney, Colin, Toubai, Tomomi, Ghosh, Amiya, Reddy, Pavan, Banerjee, Ruma, Yung, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032602/
https://www.ncbi.nlm.nih.gov/pubmed/24325345
http://dx.doi.org/10.1111/acel.12191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032602/
https://www.ncbi.nlm.nih.gov/pubmed/24325345
http://dx.doi.org/10.1111/acel.12191

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