MMTV-Espl1 Transgenic Mice Develop Aneuploid, Estrogen Receptor Alpha (ERα)-Positive Mammary Adenocarcinomas

Separase, a protease encoded by the ESPL1 gene, cleaves the chromosomal cohesin during mitosis. Separase protein and transcripts are overexpressed in a wide range of human cancers (Meyer et al., Clin Cancer Res 2009; 15: 2703-2710). To investigate the physiological consequence of Separase overexpres...

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Detalles Bibliográficos
Autores principales: Mukherjee, Malini, Ge, Gouqing, Zhang, Nenggang, Edwards, David G., Sumazin, Pavel, Sharan, Shyam K., Rao, Pulivarthi H., Medina, Daniel, Pati, Debananda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032816/
https://www.ncbi.nlm.nih.gov/pubmed/24276237
http://dx.doi.org/10.1038/onc.2013.493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032816/
https://www.ncbi.nlm.nih.gov/pubmed/24276237
http://dx.doi.org/10.1038/onc.2013.493

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