Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans

DNA lesions that block replication fork progression are drivers of cancer-associated genome alterations, but the error-prone DNA repair mechanisms acting on collapsed replication are incompletely understood, and their contribution to genome evolution largely unexplored. Here, through whole-genome se...

Descripción completa

Detalles Bibliográficos
Autores principales: Roerink, Sophie F., van Schendel, Robin, Tijsterman, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032859/
https://www.ncbi.nlm.nih.gov/pubmed/24614976
http://dx.doi.org/10.1101/gr.170431.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032859/
https://www.ncbi.nlm.nih.gov/pubmed/24614976
http://dx.doi.org/10.1101/gr.170431.113

Ejemplares similares