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Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans

DNA lesions that block replication fork progression are drivers of cancer-associated genome alterations, but the error-prone DNA repair mechanisms acting on collapsed replication are incompletely understood, and their contribution to genome evolution largely unexplored. Here, through whole-genome se...

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Detalles Bibliográficos
Autores principales:	Roerink, Sophie F., van Schendel, Robin, Tijsterman, Marcel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032859/ https://www.ncbi.nlm.nih.gov/pubmed/24614976 http://dx.doi.org/10.1101/gr.170431.113

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