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Heterozygous Ambra1 Deficiency in Mice: A Genetic Trait with Autism-Like Behavior Restricted to the Female Gender

Autism-spectrum disorders (ASD) are heterogeneous, highly heritable neurodevelopmental conditions affecting around 0.5% of the population across cultures, with a male/female ratio of approximately 4:1. Phenotypically, ASD are characterized by social interaction and communication deficits, restricted...

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Detalles Bibliográficos
Autores principales: Dere, Ekrem, Dahm, Liane, Lu, Derek, Hammerschmidt, Kurt, Ju, Anes, Tantra, Martesa, Kästner, Anne, Chowdhury, Kamal, Ehrenreich, Hannelore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032889/
https://www.ncbi.nlm.nih.gov/pubmed/24904333
http://dx.doi.org/10.3389/fnbeh.2014.00181