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Serotonin System Implication in l-DOPA-Induced Dyskinesia: From Animal Models to Clinical Investigations

In the recent years, the serotonin system has emerged as a key player in the induction of l-DOPA-induced dyskinesia (LID) in animal models of Parkinson’s disease. In fact, serotonin neurons possess the enzymatic machinery able to convert exogenous l-DOPA to dopamine (DA), and mediate its vesicular s...

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Detalles Bibliográficos
Autores principales: Carta, Manolo, Tronci, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032899/
https://www.ncbi.nlm.nih.gov/pubmed/24904522
http://dx.doi.org/10.3389/fneur.2014.00078