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The IGF Hormonal Network in Endometrial Cancer: Functions, Regulation, and Targeting Approaches

Epidemiological as well as clinical and experimental data identified the insulin-like growth factors (IGF1, IGF2) as important players in gynecological cancers in general, and endometrial tumors in particular. The IGF1 receptor (IGF1R), which mediates the proliferative and anti-apoptotic activities...

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Detalles Bibliográficos
Autores principales: Bruchim, Ilan, Sarfstein, Rive, Werner, Haim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032924/
https://www.ncbi.nlm.nih.gov/pubmed/24904527
http://dx.doi.org/10.3389/fendo.2014.00076