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The IGF Hormonal Network in Endometrial Cancer: Functions, Regulation, and Targeting Approaches
Epidemiological as well as clinical and experimental data identified the insulin-like growth factors (IGF1, IGF2) as important players in gynecological cancers in general, and endometrial tumors in particular. The IGF1 receptor (IGF1R), which mediates the proliferative and anti-apoptotic activities...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032924/ https://www.ncbi.nlm.nih.gov/pubmed/24904527 http://dx.doi.org/10.3389/fendo.2014.00076 |