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siRNA screen of ES cell-derived motor neurons identifies novel regulators of tetanus toxin and neurotrophin receptor trafficking

Neurons rely on the long-range transport of several signaling molecules such as neurotrophins and their receptors, which are required for neuronal development, function and survival. However, the nature of the machinery controlling the trafficking of signaling endosomes containing activated neurotro...

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Detalles Bibliográficos
Autores principales: Terenzio, Marco, Golding, Matthew, Schiavo, Giampietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033017/
https://www.ncbi.nlm.nih.gov/pubmed/24904285
http://dx.doi.org/10.3389/fncel.2014.00140