Cargando…

Tsg101 regulates PI(4,5)P(2)/Ca(2+) signaling for HIV-1 Gag assembly

Our previous studies identified the 1,4,5-inositol trisphosphate receptor (IP3R), a channel mediating release of Ca(2+) from ER stores, as a cellular factor differentially associated with HIV-1 Gag that might facilitate ESCRT function in virus budding. Channel opening requires activation that is ini...

Descripción completa

Detalles Bibliográficos
Autores principales: Ehrlich, Lorna S., Medina, Gisselle N., Photiadis, Sara, Whittredge, Paul B., Watanabe, Susan, Taraska, Justin W., Carter, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033031/
https://www.ncbi.nlm.nih.gov/pubmed/24904548
http://dx.doi.org/10.3389/fmicb.2014.00234