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A Novel Pax5-Binding Regulatory Element in the Igκ Locus

The Igκ locus undergoes a variety of different molecular processes during B cell development, including V(D)J rearrangement and somatic hypermutations (SHM), which are influenced by cis regulatory regions (RRs) within the locus. The Igκ locus includes three characterized RRs termed the intronic (iEκ...

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Detalles Bibliográficos
Autores principales: Levin-Klein, Rena, Kirillov, Andrei, Rosenbluh, Chaggai, Cedar, Howard, Bergman, Yehudit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033077/
https://www.ncbi.nlm.nih.gov/pubmed/24904588
http://dx.doi.org/10.3389/fimmu.2014.00240