A non-inferiority trial of an attenuated combination strategy (‘COBRA-light’) compared to the original COBRA strategy: clinical results after 26 weeks

BACKGROUND: Early, intensive treatment of rheumatoid arthritis (RA) with the combination of (initially high dose) prednisolone, methotrexate and sulfasalazine (COBRA therapy) considerably lowers disease activity and suppresses radiological progression, but is infrequently prescribed in daily practic...

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Detalles Bibliográficos
Autores principales: den Uyl, Debby, ter Wee, Marieke, Boers, Maarten, Kerstens, Pit, Voskuyl, Alexandre, Nurmohamed, Mike, Raterman, Hennie, van Schaardenburg, Dirkjan, van Dillen, Nancy, Dijkmans, Ben, Lems, Willem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Clinical and Epidemiological Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033113/
https://www.ncbi.nlm.nih.gov/pubmed/23606682
http://dx.doi.org/10.1136/annrheumdis-2012-202818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033113/
https://www.ncbi.nlm.nih.gov/pubmed/23606682
http://dx.doi.org/10.1136/annrheumdis-2012-202818

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