Cargando…
A non-inferiority trial of an attenuated combination strategy (‘COBRA-light’) compared to the original COBRA strategy: clinical results after 26 weeks
BACKGROUND: Early, intensive treatment of rheumatoid arthritis (RA) with the combination of (initially high dose) prednisolone, methotrexate and sulfasalazine (COBRA therapy) considerably lowers disease activity and suppresses radiological progression, but is infrequently prescribed in daily practic...
Autores principales: | den Uyl, Debby, ter Wee, Marieke, Boers, Maarten, Kerstens, Pit, Voskuyl, Alexandre, Nurmohamed, Mike, Raterman, Hennie, van Schaardenburg, Dirkjan, van Dillen, Nancy, Dijkmans, Ben, Lems, Willem |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033113/ https://www.ncbi.nlm.nih.gov/pubmed/23606682 http://dx.doi.org/10.1136/annrheumdis-2012-202818 |
Ejemplares similares
-
Cost-utility of COBRA-light versus COBRA therapy in patients with early rheumatoid arthritis: the COBRA-light trial
por: ter Wee, Marieke M, et al.
Publicado: (2017) -
Favourable effect of a ‘second hit’ after 13 weeks in early RA non-responders: the Amsterdam COBRA treat-to-target randomized trial
por: Hartman, Linda, et al.
Publicado: (2022) -
Long-term effects on bone mineral density after four years of treatment with two intensive combination strategies, including initially high-dose prednisolone, in early rheumatoid arthritis patients: the COBRA-light trial
por: Lucassen, M. J. J., et al.
Publicado: (2021) -
(Sub)clinical cardiovascular disease is associated with increased bone loss and fracture risk; a systematic review of the association between cardiovascular disease and osteoporosis
por: den Uyl, Debby, et al.
Publicado: (2011) -
The interferon type I signature towards prediction of non-response to rituximab in rheumatoid arthritis patients
por: Raterman, Hennie G, et al.
Publicado: (2012)