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MxA as a clinically applicable biomarker for identifying systemic interferon type I in primary Sjögren's syndrome

OBJECTIVE: To establish an easy and practical assay for identifying systemic interferon (IFN) type I bioactivity in patients with primary Sjögren's syndrome (pSS). The IFN type I signature is present in over half of the pSS patients and identifies a subgroup with a higher disease activity. This...

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Detalles Bibliográficos
Autores principales: Maria, Naomi I, Brkic, Zana, Waris, Matti, van Helden-Meeuwsen, Cornelia G, Heezen, Kim, van de Merwe, Joop P, van Daele, Paul L, Dalm, Virgil A S H, Drexhage, Hemmo A, Versnel, Marjan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033122/
https://www.ncbi.nlm.nih.gov/pubmed/23831963
http://dx.doi.org/10.1136/annrheumdis-2012-202552