Early hypersynchrony in juvenile PINK1(−)/(−) motor cortex is rescued by antidromic stimulation

In Parkinson’s disease (PD), cortical networks show enhanced synchronized activity but whether this precedes motor signs is unknown. We investigated this question in PINK1(−)/(−) mice, a genetic rodent model of the PARK6 variant of familial PD which shows impaired spontaneous locomotion at 16 months...

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Detalles Bibliográficos
Autores principales: Carron, Romain, Filipchuk, Anton, Nardou, Romain, Singh, Abhinav, Michel, Francois J., Humphries, Mark D., Hammond, Constance
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033197/
https://www.ncbi.nlm.nih.gov/pubmed/24904316
http://dx.doi.org/10.3389/fnsys.2014.00095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033197/
https://www.ncbi.nlm.nih.gov/pubmed/24904316
http://dx.doi.org/10.3389/fnsys.2014.00095

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