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Early hypersynchrony in juvenile PINK1(−)/(−) motor cortex is rescued by antidromic stimulation
In Parkinson’s disease (PD), cortical networks show enhanced synchronized activity but whether this precedes motor signs is unknown. We investigated this question in PINK1(−)/(−) mice, a genetic rodent model of the PARK6 variant of familial PD which shows impaired spontaneous locomotion at 16 months...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033197/ https://www.ncbi.nlm.nih.gov/pubmed/24904316 http://dx.doi.org/10.3389/fnsys.2014.00095 |