Characterization of Novel PI3Kδ Inhibitors as Potential Therapeutics for SLE and Lupus Nephritis in Pre-Clinical Studies

SLE is a complex autoimmune inflammatory disease characterized by pathogenic autoantibody production as a consequence of uncontrolled T–B cell activity and immune-complex deposition in various organs, including kidney, leading to tissue damage and function loss. There is a high unmet need for better...

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Detalles Bibliográficos
Autores principales: Haselmayer, Philipp, Camps, Montserrat, Muzerelle, Mathilde, El Bawab, Samer, Waltzinger, Caroline, Bruns, Lisa, Abla, Nada, Polokoff, Mark A., Jond-Necand, Carole, Gaudet, Marilène, Benoit, Audrey, Bertschy Meier, Dominique, Martin, Catherine, Gretener, Denise, Lombardi, Maria Stella, Grenningloh, Roland, Ladel, Christoph, Petersen, Jørgen Søberg, Gaillard, Pascale, Ji, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033217/
https://www.ncbi.nlm.nih.gov/pubmed/24904582
http://dx.doi.org/10.3389/fimmu.2014.00233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033217/
https://www.ncbi.nlm.nih.gov/pubmed/24904582
http://dx.doi.org/10.3389/fimmu.2014.00233

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