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Directed midbrain and spinal cord neurogenesis from pluripotent stem cells to model development and disease in a dish
Induction of specific neuronal fates is restricted in time and space in the developing CNS through integration of extrinsic morphogen signals and intrinsic determinants. Morphogens impose regional characteristics on neural progenitors and establish distinct progenitor domains. Such domains are defin...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033221/ https://www.ncbi.nlm.nih.gov/pubmed/24904255 http://dx.doi.org/10.3389/fnins.2014.00109 |