Design of Glucagon-Like Peptide-1 Receptor Agonist for Diabetes Mellitus from Traditional Chinese Medicine

Glucagon-like peptide-1 (GLP-1) is a promising target for diabetes mellitus (DM) therapy and reduces the occurrence of diabetes due to obesity. However, GLP-1 will be hydrolyzed soon by the enzyme dipeptidyl peptidase-4 (DPP-4). We tried to design small molecular drugs for GLP-1 receptor agonist fro...

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Detalles Bibliográficos
Autores principales: Tang, Hsin-Chieh, Chen, Calvin Yu-Chian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033432/
https://www.ncbi.nlm.nih.gov/pubmed/24891870
http://dx.doi.org/10.1155/2014/385120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033432/
https://www.ncbi.nlm.nih.gov/pubmed/24891870
http://dx.doi.org/10.1155/2014/385120

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