Aberrant Muscle Antigen Exposure in Mice Is Sufficient to Cause Myositis in a Treg Cell–Deficient Milieu

OBJECTIVE: Myositis is associated with muscle-targeted inflammation and is observed in some Treg cell–deficient mouse models. Because an autoimmune pathogenesis has been strongly implicated, the aim of this study was to investigate the hypothesis that abnormal exposure to muscle antigens, as observe...

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Detalles Bibliográficos
Autores principales: Young, Nicholas A, Sharma, Rahul, Friedman, Alexandra K, Kaffenberger, Benjamin H, Bolon, Brad, Jarjour, Wael N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Myositis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033530/
https://www.ncbi.nlm.nih.gov/pubmed/24022275
http://dx.doi.org/10.1002/art.38184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033530/
https://www.ncbi.nlm.nih.gov/pubmed/24022275
http://dx.doi.org/10.1002/art.38184

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