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Aberrant Muscle Antigen Exposure in Mice Is Sufficient to Cause Myositis in a Treg Cell–Deficient Milieu
OBJECTIVE: Myositis is associated with muscle-targeted inflammation and is observed in some Treg cell–deficient mouse models. Because an autoimmune pathogenesis has been strongly implicated, the aim of this study was to investigate the hypothesis that abnormal exposure to muscle antigens, as observe...
Autores principales: | Young, Nicholas A, Sharma, Rahul, Friedman, Alexandra K, Kaffenberger, Benjamin H, Bolon, Brad, Jarjour, Wael N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033530/ https://www.ncbi.nlm.nih.gov/pubmed/24022275 http://dx.doi.org/10.1002/art.38184 |
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