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The Pathology of Orthopedic Implant Failure Is Mediated by Innate Immune System Cytokines

All of the over 1 million total joint replacements implanted in the US each year are expected to eventually fail after 15–25 years of use, due to slow progressive subtle inflammation at the bone implant interface. This inflammatory disease state is caused by implant debris acting, primarily, on inna...

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Detalles Bibliográficos
Autores principales: Landgraeber, Stefan, Jäger, Marcus, Jacobs, Joshua J., Hallab, Nadim James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033543/
https://www.ncbi.nlm.nih.gov/pubmed/24891761
http://dx.doi.org/10.1155/2014/185150