A Computer Simulation Approach to Assessing Therapeutic Intervention Points for the Prevention of Cytokine-Induced Cartilage Breakdown

OBJECTIVE: To use a novel computational approach to examine the molecular pathways involved in cartilage breakdown and to use computer simulation to test possible interventions for reducing collagen release. METHODS: We constructed a computational model of the relevant molecular pathways using the S...

Descripción completa

Detalles Bibliográficos
Autores principales: Proctor, CJ, Macdonald, C, Milner, JM, Rowan, AD, Cawston, TE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Chondrocyte Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033570/
https://www.ncbi.nlm.nih.gov/pubmed/24757149
http://dx.doi.org/10.1002/art.38297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033570/
https://www.ncbi.nlm.nih.gov/pubmed/24757149
http://dx.doi.org/10.1002/art.38297

Ejemplares similares