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Cellular unfolded protein response against viruses used in gene therapy

Viruses are excellent vehicles for gene therapy due to their natural ability to infect and deliver the cargo to specific tissues with high efficiency. Although such vectors are usually “gutted” and are replication defective, they are subjected to clearance by the host cells by immune recognition and...

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Detalles Bibliográficos
Autores principales: Sen, Dwaipayan, Balakrishnan, Balaji, Jayandharan, Giridhara R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033601/
https://www.ncbi.nlm.nih.gov/pubmed/24904562
http://dx.doi.org/10.3389/fmicb.2014.00250