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Size Does Matter: Why Polyploid Tumor Cells are Critical Drug Targets in the War on Cancer
Tumor evolution presents a formidable obstacle that currently prevents the development of truly curative treatments for cancer. In this perspective, we advocate for the hypothesis that tumor cells with significantly elevated genomic content (polyploid tumor cells) facilitate rapid tumor evolution an...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033620/ https://www.ncbi.nlm.nih.gov/pubmed/24904834 http://dx.doi.org/10.3389/fonc.2014.00123 |