Insights into the Biosynthesis of 12-Membered Resorcylic Acid Lactones from Heterologous Production in Saccharomyces cerevisiae

[Image: see text] The phytotoxic fungal polyketides lasiodiplodin and resorcylide inhibit human blood coagulation factor XIIIa, mineralocorticoid receptors, and prostaglandin biosynthesis. These secondary metabolites belong to the 12-membered resorcylic acid lactone (RAL(12)) subclass of the benzene...

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Detalles Bibliográficos
Autores principales: Xu, Yuquan, Zhou, Tong, Espinosa-Artiles, Patricia, Tang, Ying, Zhan, Jixun, Molnár, István
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033647/
https://www.ncbi.nlm.nih.gov/pubmed/24597618
http://dx.doi.org/10.1021/cb500043g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033647/
https://www.ncbi.nlm.nih.gov/pubmed/24597618
http://dx.doi.org/10.1021/cb500043g

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