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A Small Molecule Compound Targeting STAT3 DNA-Binding Domain Inhibits Cancer Cell Proliferation, Migration, and Invasion

[Image: see text] Signal transducer and activator of transcription 3 (STAT3) plays important roles in multiple aspects of cancer aggressiveness including migration, invasion, survival, self-renewal, angiogenesis, and tumor cell immune evasion by regulating the expression of multiple downstream targe...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Dong, Zizheng, Wang, Fang, Peng, Hui, Liu, Jing-Yuan, Zhang, Jian-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033648/
https://www.ncbi.nlm.nih.gov/pubmed/24661007
http://dx.doi.org/10.1021/cb500071v