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Diastereoselective Three-Component Synthesis of β-Amino Carbonyl Compounds Using Diazo Compounds, Boranes, and Acyl Imines under Catalyst-Free Conditions

[Image: see text] Diazo compounds, boranes, and acyl imines undergo a three-component Mannich condensation reaction under catalyst-free conditions to give the anti β-amino carbonyl compounds in high diastereoselectivity. The reaction tolerates a variety of functional groups, and an asymmetric varian...

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Detalles Bibliográficos
Autores principales: Luan, Yi, Yu, Jie, Zhang, Xiaowei, Schaus, Scott E., Wang, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033649/
https://www.ncbi.nlm.nih.gov/pubmed/24787904
http://dx.doi.org/10.1021/jo5003505