Teaching ‘Old’ Polymyxins New Tricks: New-Generation Lipopeptides Targeting Gram-Negative ‘Superbugs’

[Image: see text] The antimicrobial lipopeptides polymyxin B and E (colistin) are being used as a ‘last-line’ therapy for infections caused by multidrug-resistant Gram-negative pathogens. Polymyxin resistance implies a total lack of antibiotics for the treatment of life-threatening infections caused...

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Detalles Bibliográficos
Autores principales: Velkov, Tony, Roberts, Kade D., Nation, Roger L., Wang, Jiping, Thompson, Philip E., Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033650/
https://www.ncbi.nlm.nih.gov/pubmed/24601489
http://dx.doi.org/10.1021/cb500080r

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033650/
https://www.ncbi.nlm.nih.gov/pubmed/24601489
http://dx.doi.org/10.1021/cb500080r

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