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Cysteine-Conjugated Metabolites of Ginger Components, Shogaols, Induce Apoptosis through Oxidative Stress-Mediated p53 Pathway in Human Colon Cancer Cells

[Image: see text] Shogaols, the major constituents of thermally processed ginger, have been proven to be highly effective anticancer agents. Our group has identified cysteine-conjugated shogaols (M2, M2′, and M2″) as the major metabolites of [6]-, [8]-, and [10]-shogaol in human and found that M2 is...

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Detalles Bibliográficos
Autores principales: Fu, Junsheng, Chen, Huadong, Soroka, Dominique N., Warin, Renaud F., Sang, Shengmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033655/
https://www.ncbi.nlm.nih.gov/pubmed/24786146
http://dx.doi.org/10.1021/jf501351r