Differential regulation of the α-globin locus by Krüppel-like factor 3 in erythroid and non-erythroid cells

BACKGROUND: Krüppel-like Factor 3 (KLF3) is a broadly expressed zinc-finger transcriptional repressor with diverse biological roles. During erythropoiesis, KLF3 acts as a feedback repressor of a set of genes that are activated by Krüppel-like Factor 1 (KLF1). Noting that KLF1 binds α-globin gene reg...

Descripción completa

Detalles Bibliográficos
Autores principales: Funnell, Alister PW, Vernimmen, Douglas, Lim, Wooi F, Mak, Ka Sin, Wienert, Beeke, Martyn, Gabriella E, Artuz, Crisbel M, Burdach, Jon, Quinlan, Kate GR, Higgs, Douglas R, Whitelaw, Emma, Pearson, Richard CM, Crossley, Merlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033687/
https://www.ncbi.nlm.nih.gov/pubmed/24885809
http://dx.doi.org/10.1186/1471-2199-15-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033687/
https://www.ncbi.nlm.nih.gov/pubmed/24885809
http://dx.doi.org/10.1186/1471-2199-15-8

Ejemplares similares