Brain-Derived Neurotrophic Factor in Human Subjects with Function-Altering Melanocortin-4 Receptor Variants

BACKGROUND: In rodents, hypothalamic brain-derived neurotrophic factor (BDNF) expression appears to be regulated by melanocortin-4 receptor (MC4R) activity. The impact of MC4R genetic variation on circulating BDNF in humans is unknown. OBJECTIVE: To compare BDNF concentrations of subjects with loss-...

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Detalles Bibliográficos
Autores principales: Hohenadel, Maximilian G., Thearle, Marie S., Grice, Brian A., Huang, Hui, Dai, Meng-Hong, Tao, Ya-Xiong, Hunter, Lindsay A., Palaguachi, Gladys I., Mou, Zongyang, Kim, Rachel C., Tsang, Matthew M., Haack, Karin, Voruganti, V. Saroja, Cole, Shelley A., Butte, Nancy F., Comuzzie, Anthony G., Muller, Yunhua L., Baier, Leslie J., Krakoff, Jonathan, Knowler, William C., Yanovski, Jack A., Han, Joan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033711/
https://www.ncbi.nlm.nih.gov/pubmed/24276017
http://dx.doi.org/10.1038/ijo.2013.221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033711/
https://www.ncbi.nlm.nih.gov/pubmed/24276017
http://dx.doi.org/10.1038/ijo.2013.221

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