Pathogenic potential of interferon αβ in acute influenza infection

Influenza symptoms vary from mild disease to death; however, determinants of severity are unclear. Type I interferons (IFNαβ) are recognized as key antiviral cytokines. Here we show that, surprisingly, influenza-infected 129 mice have increased lung damage, morbidity and mortality, yet higher levels...

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Detalles Bibliográficos
Autores principales: Davidson, Sophia, Crotta, Stefania, McCabe, Teresa M, Wack, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033792/
https://www.ncbi.nlm.nih.gov/pubmed/24844667
http://dx.doi.org/10.1038/ncomms4864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033792/
https://www.ncbi.nlm.nih.gov/pubmed/24844667
http://dx.doi.org/10.1038/ncomms4864

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