Olesoxime (TRO19622): A Novel Mitochondrial-Targeted Neuroprotective Compound

Olesoxime (TRO19622) is a novel mitochondrial-targeted neuroprotective compound undergoing a pivotal clinical efficacy study in Amyotrophic Lateral Sclerosis (ALS) and also in development for Spinal Muscular Atrophy (SMA). It belongs to a new family of cholesterol-oximes identified for its survival-...

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Detalles Bibliográficos
Autores principales: Bordet, Thierry, Berna, Patrick, Abitbol, Jean-Louis, Pruss, Rebecca M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033913/
https://www.ncbi.nlm.nih.gov/pubmed/27713255
http://dx.doi.org/10.3390/ph3020345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033913/
https://www.ncbi.nlm.nih.gov/pubmed/27713255
http://dx.doi.org/10.3390/ph3020345

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