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Olesoxime (TRO19622): A Novel Mitochondrial-Targeted Neuroprotective Compound

Olesoxime (TRO19622) is a novel mitochondrial-targeted neuroprotective compound undergoing a pivotal clinical efficacy study in Amyotrophic Lateral Sclerosis (ALS) and also in development for Spinal Muscular Atrophy (SMA). It belongs to a new family of cholesterol-oximes identified for its survival-...

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Detalles Bibliográficos
Autores principales:	Bordet, Thierry, Berna, Patrick, Abitbol, Jean-Louis, Pruss, Rebecca M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International 2010
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033913/ https://www.ncbi.nlm.nih.gov/pubmed/27713255 http://dx.doi.org/10.3390/ph3020345

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