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Structural Examination of 6-Methylsulphonylphenanthro-[9,10-C]-furan-1(3H)-one—A Rofecoxib Degradation Product
In the attempt to discover a new polymorph of rofecoxib (Vioxx®), an unexpected product resulted. The product was characterised by chemical composition, thermal behaviour and structure and found to be 6-methylsulphonylphenanthro-[9,10-C] furan-1(3H)-one, a photo-cyclization degradation product of ro...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Molecular Diversity Preservation International
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033914/ https://www.ncbi.nlm.nih.gov/pubmed/27713256 http://dx.doi.org/10.3390/ph3020369 |