Update on the Genetic Polymorphisms of Drug-Metabolizing Enzymes in Antiepileptic Drug Therapy

Genetic polymorphisms in the genes that encode drug-metabolizing enzymes are implicated in the inter-individual variability in the pharmacokinetics and pharmaco-dynamics of antiepileptic drugs (AEDs). However, the clinical impact of these polymorphisms on AED therapy still remains controversial. The...

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Detalles Bibliográficos
Autores principales: Saruwatari, Junji, Ishitsu, Takateru, Nakagawa, Kazuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033946/
https://www.ncbi.nlm.nih.gov/pubmed/27713373
http://dx.doi.org/10.3390/ph3082709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033946/
https://www.ncbi.nlm.nih.gov/pubmed/27713373
http://dx.doi.org/10.3390/ph3082709

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