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Suppression of Autoimmune Arthritis by Small Molecule Inhibitors of the JAK/STAT Pathway
A skewed ratio of pro-inflammatory to anti-inflammatory cytokines, elevated growth factor synthesis and T- and B-lymphocyte activation are 3 hallmarks of rheumatoid arthritis (RA) pathology. Interleukin-6 (IL-6), IL-7, IL-17, IL-12/IL-23 and growth factors, granulocyte macrophage-colony stimulating...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033991/ https://www.ncbi.nlm.nih.gov/pubmed/27713312 http://dx.doi.org/10.3390/ph3051446 |