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Suppression of Autoimmune Arthritis by Small Molecule Inhibitors of the JAK/STAT Pathway

A skewed ratio of pro-inflammatory to anti-inflammatory cytokines, elevated growth factor synthesis and T- and B-lymphocyte activation are 3 hallmarks of rheumatoid arthritis (RA) pathology. Interleukin-6 (IL-6), IL-7, IL-17, IL-12/IL-23 and growth factors, granulocyte macrophage-colony stimulating...

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Detalles Bibliográficos
Autor principal:	Malemud, Charles J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2010
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033991/ https://www.ncbi.nlm.nih.gov/pubmed/27713312 http://dx.doi.org/10.3390/ph3051446

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