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Thrombospondin-1 as a Paradigm for the Development of Antiangiogenic Agents Endowed with Multiple Mechanisms of Action

Uncontrolled neovascularization occurs in several angiogenesis-dependent diseases, including cancer. Neovascularization is tightly controlled by the balance between angiogenic growth factors and antiangiogenic agents. The various natural angiogenesis inhibitors identified so far affect neovasculariz...

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Detalles Bibliográficos
Autores principales: Rusnati, Marco, Urbinati, Chiara, Bonifacio, Silvia, Presta, Marco, Taraboletti, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034032/
https://www.ncbi.nlm.nih.gov/pubmed/27713299
http://dx.doi.org/10.3390/ph3041241