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Positive effects of methylphenidate on hyperactivity are moderated by monoaminergic gene variants in children with autism spectrum disorders

Methylphenidate (MPH) reduces hyperactive-impulsive symptoms common in children with autism spectrum disorders (ASDs), however, response and tolerability varies widely. We hypothesized monoaminergic gene variants may moderate MPH effects in ASD, as in typically developing children with attention-def...

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Detalles Bibliográficos
Autores principales: McCracken, J T, Badashova, K K, Posey, D J, Aman, M G, Scahill, L, Tierney, E, Arnold, L E, Vitiello, B, Whelan, F, Chuang, S Z, Davies, M, Shah, B, McDougle, C J, Nurmi, E L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034115/
https://www.ncbi.nlm.nih.gov/pubmed/23856854
http://dx.doi.org/10.1038/tpj.2013.23