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Data mining reveals a network of early-response genes as a consensus signature of drug-induced in vitro and in vivo toxicity
Gene signatures of drug-induced toxicity are of broad interest, but they are often identified from small-scale, single-time point experiments, and are therefore of limited applicability. To address this issue, we performed multivariate analysis of gene expression, cell-based assays, and histopatholo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034126/ https://www.ncbi.nlm.nih.gov/pubmed/24217556 http://dx.doi.org/10.1038/tpj.2013.39 |