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Perspectives of Differentiation Therapies of Acute Myeloid Leukemia: The Search for the Molecular Basis of Patients’ Variable Responses to 1,25-Dihydroxyvitamin D and Vitamin D Analogs

The concept of differentiation therapy of cancer is ~40 years old. Despite many encouraging results obtained in laboratories, both in vitro and in vivo studies, the only really successful clinical application of differentiation therapy was all-trans-retinoic acid (ATRA)-based therapy of acute promye...

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Detalles Bibliográficos
Autores principales: Marchwicka, Aleksandra, Cebrat, Małgorzata, Sampath, Preetha, Śnieżewski, Łukasz, Marcinkowska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034350/
https://www.ncbi.nlm.nih.gov/pubmed/24904835
http://dx.doi.org/10.3389/fonc.2014.00125